Adult Stem Cells

By Mamta Singh

Here is one more reason why you should put on that workout gear and exercise. To the already long list of benefits that can be availed from following a regular workout routine, a new study conducted by the researchers at McMaster University, Canada now adds another benefit. And this benefit may be had even if you exercise only moderately every other day of the week.

It seems that the body’s influential stem cells are urged, during an exercise session, to develop into a bone cell rather than a fat cell. (1)

In other words, the benefit also doubles up as the reason why people who work out have better bone density and are fitter instead of flabby or with low bone mass.

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Advances in the study of stem cells have fueled hopes that someday, via regenerative medicine, doctors could restore aging people’s hearts, livers, brains and other organs and tissues to a more youthful state. A key to reaching this goal — to be able to provide stem cells that will differentiate into other types of cells a patient needs — appears to lie in understanding “epigenetics,” which involves chemical marks stapled onto DNA and its surrounding protein husk by specialized enzyme complexes inside a cell’s nucleus. These markings produce long-lasting changes in genes’ activity levels within the cell — locking genes into an “on” or “off” position. Epigenetic processes enable cells to remain true to type (a neuron, for instance, never suddenly morphs into a fat cell) even though all our cells, regardless of type, share the same genetic code. But epigenetic processes also appear to play a critical role in reducing cells’ vitality as they age.

Bruce Goldman of the Office of Communication & Public Affairs recently talked to Thomas Rando, MD, PhD, professor of neurology and neurological sciences and director of the Glenn Laboratories for the Biology of Aging at Stanford, about the prospects for rejuvenating tissues by reprogramming the epigenetic settings of stem cells within those tissues. Rando and Howard Chang, MD, PhD, professor of dermatology, are co-authors of a review article on this subject published Jan. 20 in Cell.

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Sarah Knauss, famous for being among the oldest people in the world until her death at the age of 119, might have had more than just “good genes.” Dana-Farber’s Wayne Marasco, MD, PhD, says that adult stem cells – known for their healing and regenerative properties – might hold the key to a long and healthy life.

Marasco shared his expertise on the subject at the recent International Vatican Conference on Adult Stem Cells in Vatican City, Italy, an event attended by a select group of cardinals, clergy, and leading researchers and physicians from around the world.

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Pro-lifers and Gov. Scott Walker say they’re a better way to go. Scientists beg to differ

By Nathan J. Comp

Saul Richman’s prospects were not good. In November 2009, after what he thought was the flu turned out to be leukemia, he underwent a week of 24-hour chemo. When that didn’t work, more chemo sent the cancer into remission, but with an 80% chance that it would return. Richman needed a bone-marrow transplant and, even then, his prospects were grim.

“Once you have leukemia, it’s already kind of too late,” says Karen, Saul’s wife of 41 years.

In May, an international donor search failed to find a match. The Richmans’ time and options were running out. Then something unexpected happened.

“We were referred to UW,” Karen recalls. “They said, ‘There’s one more thing we’ve been having good results with.’ We thought we were going there for a bone-marrow transplant, but they said, ‘No, this is something completely different.’”

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By BRADLEY J. FIKES

Embryonic stem cell therapy is fading out in favor of treatment with adult stem cells, according to an editorial in the peer-reviewed, open-access Journal of Translational Medicine.

The editorial says studies are now showing that adult stem cells are naturally superior for treating diseases or injuries than embryonic stem cells or their close cousins, induced pluripotent stem cells. It was written in the aftermath of the decision by Geron Corp. to abandon development of embryonic stem cell therapy. That abandonment, the editorial argues, was misinterpreted by the media as a setback for stem cell therapy, when in fact great progress is being made with non-embryonic stem cell therapy.

Its three authors include Thomas Ichim of San Diego-based MediStem Inc, which is developing therapy with a “universal donor” adult stem cell. That is a commercial conflict of interest I’m noting for the record, although it doesn’t discredit Ichim as a source. Conflicts of interest are common in science, because knowledgeable people often have commercial ties to their field of research.

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Three men have been arrested and a fourth is being sought by the FBI in connection with what investigators say was a $1.5-million Texas-based scheme to illegally market and sell stem cell treatments to patients with terminal diseases.

“Protecting the public from unproven and potentially dangerous drug and medical procedures is very important,” said Kenneth Magidson, U.S. attorney for the Houston-based southern district of Texas, in an online statement. “This office will continue to prosecute violations involving threats to the public health.”

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“LAKELAND – A Lakeland family believes an experimental stem cell treatment is giving their son the precious gift of sight.

Xavier Carballo was born with a condition making it very difficult for him to see.

Back in 2008, Xavier was comfortable singing “Besame Mucho” while sitting in front of his keyboard. But it was a much different story when the 5-year-old was led outside to the swing set.”

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“(CBS) Have scientists finally discovered the fountain of youth? Results from a new study suggest a way to stop aging might not be too far-fetched after all.

Researchers at the University of Pittsburgh have developed a stem cell treatment that significantly stalls aging and increases life span – if you’re a mouse. But the study, which shows how stem cells influence aging, may provide new clues on aging that will one day help humans.”

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“TORONTO – Eyes have been called the window to the soul, but they are also proving to be a potential wellspring for regenerative medicine.

Researchers say they have discovered a new source of stem cells at the back of the eye, which they hope may one day provide a way to repair the damage from age-related macular degeneration, or AMD, the leading cause of vision loss in people over 60.”

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“Stem cell therapies offer the potential to treat diseases or conditions for which few treatments exist.

Stem cells, sometimes called the body’s “master cells,” are the precursor cells that develop into blood, brain, bones and all of your organs. Their promise in medical treatments is that they have the potential to repair, restore, replace and regenerate cells that could then be used to treat many medical conditions and diseases.”

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Restore and Revitalize Your Skin’s Youthful Vibrance At The Cellular Level With This Breakthrough Renewal Serum. Learn more about Adult Stem Cells, Adult Stem Cell Supplements, Stem Cell Enhancer and Circulation Enhancer.