Adult Stem Cells
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“LAKELAND – A Lakeland family believes an experimental stem cell treatment is giving their son the precious gift of sight.
Xavier Carballo was born with a condition making it very difficult for him to see.
Back in 2008, Xavier was comfortable singing “Besame Mucho” while sitting in front of his keyboard. But it was a much different story when the 5-year-old was led outside to the swing set.”
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“(CBS) Have scientists finally discovered the fountain of youth? Results from a new study suggest a way to stop aging might not be too far-fetched after all.
Researchers at the University of Pittsburgh have developed a stem cell treatment that significantly stalls aging and increases life span – if you’re a mouse. But the study, which shows how stem cells influence aging, may provide new clues on aging that will one day help humans.”
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“TORONTO – Eyes have been called the window to the soul, but they are also proving to be a potential wellspring for regenerative medicine.
Researchers say they have discovered a new source of stem cells at the back of the eye, which they hope may one day provide a way to repair the damage from age-related macular degeneration, or AMD, the leading cause of vision loss in people over 60.”
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“Stem cell therapies offer the potential to treat diseases or conditions for which few treatments exist.
Stem cells, sometimes called the body’s “master cells,” are the precursor cells that develop into blood, brain, bones and all of your organs. Their promise in medical treatments is that they have the potential to repair, restore, replace and regenerate cells that could then be used to treat many medical conditions and diseases.”
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“New research highlights the possibility of reversing ageing in the central nervous system for multiple sclerosis (MS) patients. The study is published today, 06 January, in the journal Cell Stem Cell.
As we get older, our bodies’ ability to regenerate decreases. This is not only true for our skin (which is evident in the wrinkles that develop as we age) but also true for other tissues in the body, including the regenerative processes in the brain. For diseases which often span several decades and are affected by regenerative processes, such as multiple sclerosis, this can have massive implications.”
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Jerome Zack — a scientist with the University of California, Los Angeles, Jonsson Comprehensive Cancer Center and the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research — said the tests, conducted on mice, prove blood stem cells can be genetically altered in a living organism to fight cancer.
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When a muscle is damaged, dormant adult stem cells called satellite cells are signaled to “wake up” and contribute to repairing the muscle. University of Missouri researchers recently found how even distant satellite cells could help with the repair, and are now learning how the stem cells travel within the tissue. This knowledge could ultimately help doctors more effectively treat muscle disorders such as muscular dystrophy, in which the muscle is easily damaged and the patient’s satellite cells have lost the ability to repair.
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Q: Now that Geron has discontinued its embryonic stem cell research, while at the same time adult stem cell experiments have had a number of successful trials, what does this mean for the stem cell debate?
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The term “stem cell” may call to mind controversy, but ethical debates about human embryos are a separate matter. Stem cells are found in adults, too. They are called the building blocks of the body, because they begin as a wild card but can divide into specialized cells that do different jobs, like make cartilage, bone and muscle. They are being researched around the world for treatment of human disorders such as spinal injuries, heart problems and auto-immune diseases.
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From a historical perspective, the Obama administration has invested thus far more than $430 million and California has invested $3 billion (Prop. 71 since 2004) in this “scientific” destruction of human embryos with no successful clinical trials anywhere in the world using embryos in stem cell research. However, with the use of adult stem cells, there are currently hundreds of human patients being successfully treated for more than 70 conditions entailing neural degenerative diseases and injuries (including spinal cord), varieties of cancers, auto-immune diseases, immunodeficiencies, cardiovascular conditions, ocular diseases, wounds and bone repairs and replacements, anemias and other blood diseases, metabolic disorders, as well as diseases of the liver and bladder (www.stemcellresearchfacts.org).
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